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Sildenafil citrate: Chemical synthesis and pharmaceutical characteristics

Sildenafil > sildenafil 50g


Do not remove the film from the pouch unless ready for immediate use. Do not handle the oral film with wet hands. See the Vybrique Prescribing Information for more information about how to take sildenafil oral film.

  • Sildenafil 50mg is a medication used to treat erectile dysfunction.
  • It belongs to the class of phosphodiesterase type 5 inhibitors.
  • Typical starting dose is 50mg taken about an hour before activity.
  • Sildenafil works by increasing blood flow to the penis.
  • It can help achieve and maintain an erection suitable for sex.
  • The effects of sildenafil usually last around 4 to 6 hours.
  • Avoid taking sildenafil with high-fat meals as it may delay absorption.
  • Common side effects include headaches, flushing, and nasal congestion.
  • Patients should not exceed one dose within a 24-hour period.
  • It is important to consult a doctor before using sildenafil, especially if on other medications.
  • Sildenafil may cause dizziness; avoid driving until effects are known.

Take sildenafil exactly as it was prescribed for you. Follow all directions on your prescription label and read all medication guides or instruction sheets.

What is Viagra?

Toggle navigation Shop Home Contact us My Cart Sign in Products Sildenafil 50mg Tablets (Nelgra) Default Pricelist Previous Next Sildenafil 50mg Tablets (Nelgra) 40.00 KSh 40.00 KSh 40.0 KES 40.00 KSh Product not available Add to Cart Price Per 4 Tablet's Alternative Products: Sildenafil 50mg Tablets (Aphrodis) Sildenafil 50mg Tablets (Hot) Sildenafil 50mg Tablets (Negax) Pronunciation: sil-DEN-a-fil Generic name: sildenafil Brand names: Revatio, Viagra, Vybrique Dosage form: tablets (20 mg; 25 mg, 50 mg, 100 mg), injection (10 mg/12.5 mL), oral suspension (10 mg/mL), oral film (25 mg, 50 mg, 75 mg, 100 mg) Drug classes: Agents for pulmonary hypertension, Impotence medications Sildenafil is used to treat erectile dysfunction (ED) in adult men or pulmonary arterial hypertension (PAH) in adults and children, depending on the brand or formulation. Sildenafil tablets (25 mg, 50 mg, 100 mg; Viagra, generic) and sildenafil oral film (25 mg, 50 mg, 75 mg, 100 mg; Vybrique) are used for ED. Sildenafil tablets (20 mg; Revatio, generic), sildenafil oral suspension (Revatio, generic), and sildenafil injection (Revatio, generic) are used for PAH. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor, which breaks down cyclic GMP and enhances nitric oxide (NO) -mediated smooth muscle relaxation. In erectile dysfunction (ED), this increases blood flow to penile tissue, facilitating an erection.

Adjusting Your Sildenafil Dosage Over Time

In pulmonary arterial hypertension (PAH), it dilates pulmonary vessels by the same mechanism, reducing pulmonary blood pressure and improving exercise capacity. Sildenafil first gained FDA approval on March 27, 1998. Do not take sildenafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers". Taking sildenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure. Some medicines can cause unwanted or dangerous effects when used with sildenafil.

Your questions answered

Tell your doctor about all your current medicines, especially riociguat (Adempas). The most common side effects of sildenafil tablets for ED are: Abnormal vision, such as changes in color vision (such as having a blue color tinge) andblurred vision The most common side effects of sildenafil oral film for ED are: Abnormal vision, such as changes in color and blurred vision The most common side effects of sildenafil tablets/ oral suspension, and injection for PAH are: Sildenafil can cause the following serious side effects. If you have an erection that lasts more than 4 hours, get medical help right away. If it is not treated right away, priapism can permanently damage your penis. Sildenafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. Do not change your dose or stop taking this medicine on your own. Take sildenafil lovegra sildenafil tablet or oral suspension 3 times a day, about 4 to 6 hours apart. Take at approximately the same times every day. Sildenafil oral suspension will be mixed for you by your pharmacist.

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Do not mix with other medicines or flavorings.

Toxicity and side effects

Tell your doctor if you get more short of breath after you start sildenafil. More shortness of breath than usual may be due to your underlying medical condition. Do not take Viagra while also taking Revatio. Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the sildenafil tablets 125 possible side effects of sildenafil.

Vybrique Oral Film

Have allergies to sildenafil, Viagra, Revatio, Vybrique, or any of the ingredients in the sildenafil formulation you are taking Take other medicines for pulmonary arterial hypertension, such as riociguat (Adempas) Take other medicines for pulmonary arterial hypertension, such as riociguat (Adempas) Take other medicines that lower your blood pressure, such as nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs that also contain nitrates, such as "poppers". To make sure sildenafil is safe for you, tell your healthcare provider about all your medical conditions, including if you have: Or have had heart problems such as a heart attack, irregular heartbeat, angina, chest pain, narrowing of the aortic valve, or heart failure Had heart surgery within the last 6 months Low blood pressure, or high blood pressure that is not controlled A physical deformity of the penis (such as Peyronie's disease) Been told you should not have sexual intercourse for health reasons and you are a male Had an erection that lasted for more than 4 hours Problems with your blood cells, such as sickle cell anemia, multiple myeloma, or leukemia Retinitis pigmentosa, a rare genetic (runs in families) eye disease Ever had severe vision loss, including an eye problem called non-arteritic anterior ischemic optic neuropathy (NAION) Kidney problems or are having kidney dialysis Are pregnant or intending to become pregnant (for patients with PAH) Are breastfeeding or intending to breastfeed (for patients with PAH). Sildenafil for ED is not approved for males <18 years old. Sildenafil is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Taking Viagra with food

Women with pulmonary arterial hypertension should not stop taking sildenafil without talking to their doctor if they discover they are pregnant. It is not known whether sildenafil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breastfeeding a baby. Women with pulmonary arterial hypertension should not stop taking sildenafil without talking to their doctor. Take sildenafil oral tablets exactly as your healthcare provider tells you to take it. Shake the oral suspension (liquid) before you measure a dose.

How it works

This has occurred in a small number of people taking sildenafil, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old. Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION). Stop taking sildenafil and call your healthcare provider right away if you havesudden vision loss in one or both eyes. Some people may also have ringing in their ears (tinnitus) or dizziness. If you have these symptoms, stop taking sildenafil and contact a doctor right away.

Who should not take sildenafil?

In addition, heart attack, stroke, irregular heartbeats, and death have happened rarely in people taking sildenafil. Most, but not all, of these people had heart problems before taking this medicine. It is not known if sildenafil caused these problems. Tell all your healthcare providers that you take sildenafil. If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took sildenafil.

Side effects and risks

Stop sexual activity and get medical help right away if you get symptoms such as chest pain, dizziness, or nausea during sex. Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease. Sildenafil does not protect you or your partner sildenafil 200 mg from getting sexually transmitted diseases, including Human Immunodeficiency Virus (HIV). Sildenafil may cause low blood pressure, which may cause you to feel faint or dizzy. Lie down if you feel faint or dizzy. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). When sildenafil is used for ED, it is used as needed, so you are not likely to miss a dose. If you are taking sildenafil for PAH and you miss a dose, take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. If you take too much sildenafil, call your doctor or go to the nearest hospital emergency room. Drinking alcohol with sildenafil can cause side effects. Grapefruit juice and products may interact with sildenafil, leading to unwanted side effects.

  • Sildenafil 50mg dosage is generally effective and well-tolerated.
  • It is recommended to use sildenafil at the same time each day if needed regularly.
  • Never share your medication with others; it is prescribed specifically for you.
  • Persistent or severe side effects should be reported to a healthcare provider.
  • Electronic and physical stores require a prescription for purchasing sildenafil.
  • Proper use of sildenafil can improve confidence and quality of life.
  • The medication may interact with certain antihypertensive drugs.
  • Lifestyle factors like smoking cessation can improve erectile function.
  • Sildenafil is not a hormone therapy; it acts locally in the blood vessels.
  • It should not be used with recreational drugs containing nitrates or amyl nitrates.
  • Medical history

Avoid using any other medicines to treat impotence, such as alprostadil or yohimbine, without first talking to your doctor. Tell your healthcare provider about all the medicines you take, including prescription and over-the-countermedicines, vitamins, and herbal supplements.

Aspect Information Provided Source or Reference Additional Notes
Proper use Take 30-60 minutes before activity Medical guidelines Avoid excessive dosage
Potential side effects Headache, flushing, dizziness Patient information leaflet Consult doctor if severe effects occur
Storage and disposal Store in a cool, dry place; dispose of unused medicine safely Pharmacist advice Prevent misuse or accidental ingestion

Sildenafil may affect the way other medicines work, and other medicines may affect the way sildenafil works, causing side effects.

Related/similar drugs

Your healthcare provider will tell you how much to take and when to take it. Your healthcare provider may change your dose if needed. You may take sildenafil between 30 minutes to 4 hours before sexual activity if needed. If you take sildenafil after a high-fat meal (such as a cheeseburger and fries), sildenafil may take a little longer to start working. If you accidentally take too much sildenafil, call your doctor or go to the nearest hospital emergency room right away.

When and How to Take Sildenafil for Best Results

Sildenafil can help you have an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect of sildenafil. Take sildenafil oral film (Vybrique) exactly as your healthcare provider tells you to take it.

Problems solved by technology

Your healthcare provider will tell you how much sildenafil to take and when to take it. Take sildenafil by mouth about 1 hour before sexual activity. You may take sildenafil between 30 minutes and 4 hours before sexual activity if needed. Do not take more than once a day. If you take too much sildenafil, call your healthcare provider or go to the nearest hospital emergency room right away.